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  • Based on the preliminary results obtained for the Pt(II) complex [Pt(OXA)(DACHEX)] (an oxaliplatin-analogue possessing a double bond in the 4-position of the 1,2-diaminocyclohexane ring), which proved to have a cytotoxic activity better than that of cisplatin and comparable to or better than that of oxaliplatin and to be equally active against LoVo and LoVo-OXP cells, in this paper we have extended the investigation to corresponding Pt(IV) derivatives having different ligands in the axial positions.
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