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Compound 4 exhibited a reduction potential in the high range (Ep of −0.72, intermediate between those of 5, −0.82, and 6, −0.48), but its lipophilicity (logP of −1.65) was second only to that of compound 3 and was greater than that of compounds 5 and 6 (logP of −2.03 and −2.39, respectively); as a consequence, 4 had greater cytotoxicity than 5 and 6.
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