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The genetic loci considered to be important include H2D (termed Rmp3, resistance to mousepox), on chromosome 17 [90]; the C5 genes (Rmp2, on chromosome 2); Rmp1, localized to a region on chromosome 6 encoding the NK cell receptor NKR-P1 alloantigens [91]; the nitric oxide synthase 2 locus on chromosome 11 [92]; and the signal transducer and activator of transcription 6 locus on chromosome 10 [93].
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