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Hemopoietic cell kinase (HCK) metagene and MHC-II metagene, surrogate markers of cells belonging to the monocyte/myeloid lineage and of antigen-presenting cells, respectively, were found to be significantly higher expressed in ECM3 tumors (p < 0.001), but not associated with response either in cases of the chemotherapy arm or in those receiving trastuzumab (Figure S2).
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