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The marked increase in the concentration of cytokines was found only during the active phase of the drug-related inflammatory process for IL-1ra, IL-6, IL-10, interferon (IFN)-γ, interferon-γ inducible protein-10 (IP-10)/CXCL10, monocyte chemoattractant protein-1 (MCP-1)/CCL2, and macrophage inflammatory protein-1α (MIP-1α)/CCL3 (figure 3).
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