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  • EphA4 deletion under the CAG promoter allowed us to reach a ubiquitous reduction of EphA4 mRNA and protein to 50% within the lumbar spinal cord in EphA4 CAG-CreER (CAG-EphA4) mice, and a loss of more than 85% in EphA4 CAG-CreER (CAG-EphA4) mice 10 days after Tamoxifen administration as compared with controls (Fig. 1A-D and Supplementary Data, Fig. S1A,B).
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