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  • Comparing the AUC of glucose excursion curves in the disease animal models with the AUC of their correspondent age-matched controls, it was observed that the groups HF 19 weeks, HF+STZ, HSu 16 weeks, HF+HSu 25 weeks, and Zucker 17 and 23 weeks presented glucose intolerance (HF 19 weeks = 24,406.29 ± 393.89; HF+STZ = 31,330.83 ± 1625.33; HSu 16 weeks = 21,502.75 ± 720.46; HF+HSu 25 weeks = 24,969.63 ± 635.89; Zucker 17 weeks = 56,526.00 ± 5115.70; Zucker 23 weeks = 69,514 ± 1414; CTL 19 weeks = 19,668 ± 380.34; CTL for HF+STZ = 23,427.83 ± 567.41; CTL 16 weeks = 20,689.80 ± 836.43; CTL 25 weeks = 21,986 ± 368.85; lean 17 weeks = 16,849 ± 616.37; lean 23 weeks = 16,208 ± 0.00 mg/dl*min).
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