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  • In vCJD a body of evidence including the transmission of vCJD through blood transfusion (Peden et al., 2004; Hewitt et al., 2006; Wroe et al., 2006; Gillies et al., 2009), detection of PrP through PMCA (Bougard et al., 2016) and in vivo infectivity studies have shown that prion infectivity can be present without CNS involvement (Bishop et al., 2013).
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