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The second group of CSF-MIF measurements were from 18 patients who had been diagnosed with CIS (n = 9) / MS (n = 9) but had not presented with an acute clinical relapse within the preceding 4 weeks or received any steroids within the 8 weeks (CIS/MS without acute relapse = CIS/MS w/o) prior to study inclusion (mean [SD] latency between last relapse and lumbar puncture = 31 [39] months).
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