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The individual membrane current components that were modeled were (i) three inward currents: L-type and T-type Ca2+ currents (ICaL and ICaT), a hyperpolarization-activated current (Ih); (ii) six outward K+ currents: two voltage-gated K+ currents (IKv1, IKCNQ), an ATP-dependent K+ current (IKATP) and three Ca2+-activated K+ currents (IBK(Ca), ISK(Ca), IIK(Ca)); and (iii) an outward back-ground leak current (ILeak).
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