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The variation of each gating variable (m or h) can be expressed by first order differential Eqs (3 and 4) dm(Vm,t)dt=m∞(Vm)−m(Vm,t)τm(3) dh(Vm,t)dt=h∞(Vm)−h(Vm,t)τh(4) where m∞ and h∞ are the steady-state values, τm and τh the time constants, all being functions of voltage and/or intracellular Ca2+ ionic concentrations.
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