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  • 478 (xsd:integer)
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  • dVmdt=−1Cm(ICa+IK+Ih+Ileak+Istim)(1)All membrane currents except large conductance (BK) Ca2+-dependent activation K+ channel were modeled using the Hodgkin-Huxley formalism: I=g¯[m(Vm,t,[Ca2+]i)]xh[(Vm,t,[Ca2+]i)]y(Vm−Erev)(2) where g¯ is maximum ionic conductance, Erev is the ion’s reversal potential, the dimensionless gating variable ‘m’ describes the time/voltage/Ca2+-dependent activation and ‘h’ is the time/voltage/Ca2+-dependent inactivation of the channel conductance.
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