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In addition, it has been shown that the phase of the menstrual cycle affects corticosterone and cortisol levels (Bangasser and Valentino, 2014; Toufexis et al., 2014), and combinatorial changes in transcription occur with activation of the estrogen receptor (ER) and GR that do not occur with either in isolation (Whirledge and Cidlowski, 2013; Whirledge et al., 2013; Deak et al., 2015).
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