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  • The risk of AD in general is increased with chronic stress, which in pre-clinical models is often defined as daily stressors applied for 3 weeks or greater (Catania et al., 2009; Dong and Csernansky, 2009; Khalsa, 2015; Machado et al., 2014; Bao et al., 2008; Pardon and Rattray, 2008; Swaab et al., 2005; Wilson et al., 2007).
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