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To calculate the cost-effectiveness over 10 years of each vaccination option per human death averted, we used the following formula: Costperhumandeathaverted=Costsofdogvaccinationprogram−costsincurredwithnovaccinationprogramNumberofhumandeathswithoutvacciantionprogram−humandeathswithvaccinationprogram For estimates of cost per case averted over more than 1 year (e.g., 10 years), each component of the formula was first summed, then the overall result calculated (e.g., for a 10 year cost of human death averted, the 10 year cost for dog vaccination program was summed separately, then added into the formula).
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