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To do this, we grouped the short series Mr corresponding to the pre-infection phase by using the k-means algorithm (kmeans command in Matlab performed with squared Euclidean distance) with the five statistical values (Mrmin, Mrq1, Mrmed, Mrq3, Mrmax), which assigned the input observations into k clusters through step-wise cluster centroid estimation based on optimisation of within- and between-cluster dispersion [19].
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