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The present investigation is a cross-sectional analysis on baseline data within the frame of the PREDIMED-PLUS study, a 6-year multicenter, randomized, parallel-group, primary prevention clinical trial conducted in Spain to assess the effect on CVD morbimortality of an intensive weight loss intervention program based on an energy-restricted traditional Mediterranean diet, PA promotion and behavioral support, in comparison with an usual care intervention only with energy-unrestricted Mediterranean diet (control group).
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