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  • Insulin sensitivity (IS) was calculated using the equation developed and validated with the euglycemic-hyperinsulinemic clamp used in the SEARCH diabetes in youth study. [18] The following equation was used to measure IS: IS = exp [4.64725–0.02032 x waist (cm) - 0.09779 x [HbA1C(%)] - 0.00235 x TG (mg/dL)].
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