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We created a database for all the districts of Nigeria for the period 2004−2014 that included variables describing routine immunisation coverage, serotype-2 population immunity, the number of tOPV SIAs in the preceding 6 months (since VDPV2 emergence will precede detection in a child with AFP by about this time period, based on observed genetic divergence from the Sabin virus [23,24]), and demographic variables including mean household size, population density and annual number of births (Section B in S1 Text).
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