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All the rats were housed in individual plastic home cages lined with wood shavings and maintained on a 12:12 dark-light cycle (with the lights on from 06:00 to 18:00), with an ambient temperature of 22 ± 1°C, and free access to tap water and the standard laboratory rat diet (Rat/Mouse/Hamster chow, 1000 Formula, 12.9 kJ/g; Agway Prolab, Syracuse, NY), unless otherwise specified.
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