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  • The expression levels of various defensins were different in the WT and cKO oviducts, but there was not an overall up- or down-regulation of defensin expression in the cKO oviduct, and even direct application of defensins to embryos in vitro did not cause embryo lysis (Figure 6-figure supplement 1), so it is unlikely that defensins alone explain the embryo lysis phenotype.
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