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  • We developed Hi-Corrector, an easy-to-use, open source implementation of the Hi-C data normalization algorithm. The package is freely available at http://zhoulab.usc.edu/Hi-Corrector/. We developed Hi-Corrector, a scalable and memory-efficient package for bias removal in HiC data. Hi-Corrector can run on any single computer or a computer cluster with limited memory size to complete the task. Therefore, Hi-Corrector is a timely resource addressing the challenge of normalizing high-resolution Hi-C data.
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