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nif:beginIndex
  • 0 (xsd:integer)
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  • 547 (xsd:integer)
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  • We represent reversible binding of RPTOR to EIF4EBP1 using two unidirectional rules, as follows: RPTOR(RNC,ulk1,S792~0,S855_Ser859~0)+EIF4EBP1(RCR,S65_T70~0)-> \ RPTOR(RNC!1,ulk1,S792~0,S855_Ser859~0).EIF4EBP1(RCR!1,S65_T70~0)a4(4A) RPTOR(RNC!1).EIF4EBP1(RCR!1)->RPTOR(RNC)+EIF4EBP1(RCR)d4(4B) The first rule, Equation (4A), indicates that RPTOR, when free of ULK1 (which interacts with an undefined region in RPTOR that we refer to as ulk1) and not phosphorylated at S792, S855, and S859, is able to associate with EIF4EBP1 with rate constant a4.
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