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We represent reversible binding of RPTOR to ULK1 using three unidirectional rules, as follows: RPTOR(RNC,ulk1,S792~0,S855_Ser859~0)+ULK1(straptor)-> \ RPTOR(RNC,ulk1!1,S792~0,S855_Ser859~0).ULK1(straptor!1)a3(3A) RPTOR(ulk1!1).ULK1(straptor!1)->RPTOR(ulk1)+ULK1(straptor)d3(3B) RPTOR(ulk1!1,S792~P,S855_Ser859~PP).ULK1(straptor!1)-> \ RPTOR(ulk1,S792~P,S855-9~PP)+ULK1(straptor)d3max(3C) Note that unidirectionality is indicated by the symbol “->.” A unidirectional rule is only read from left to right.
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