nif:isString
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Each rule indicates that AMPK kinase activity requires 1) phosphorylation at T172 in the kinase domain of the PRKAA2 isoform of the α subunit (or equivalently, phosphorylation at T183 in the kinase domain of the PRKAA1 isoform of the α subunit), 2) the absence of phosphorylation at S/T residues in the α subunit outside the kinase domain, and 3) association of AMPK with ULK1, which is mediated by the ulk1 and stampk sites in AMPK and ULK1, respectively.
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