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  • We investigated three levels of time-varying covariate adjustment: Model 1 was adjusted for participant age at baseline; Model 2 was additionally adjusted for sex, race, education, cognitive functioning, limitations in ADLs and IADLS, depressive symptoms, body mass index, exercise, smoking status, and alcohol use; and Model 3 was additionally adjusted for chronic health conditions (cancer, cardiovascular disease, cerebrovascular disease, diabetes, hypertension, or arthritis).
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