DprE1-T25 and DprE1-T18, DprE1-T25 and DprE1-T18 fusions, as well as all four pairs of hybrid proteins co-expressing DprE2 led to a strong lacZ induction (ranged between 291 ± 33 and 1156 ± 54 Miller units), significantly exceeding the negative control (Fig. S [3]).