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  • Although autistic children exhibited no physical features of GH deficiency, particularly with respect to anthropometric parameters, these findings do not rule out the involvement of GH deficiency for the following reasons: first, the role of GH is not limited to physical growth; second, the significantly elevated androgen levels in autistic children and their correlation with growth parameters, along with the known anabolic effects of androgens [35], can compensate for the effects of GH deficiency on physical growth; and third, even if GH was deficient, the GH receptors of autistic children might have an increased sensitivity that masks the physical effects of GH deficiency.
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