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  • A non-restrictive quasi-steady state approximation (QSSA) method is applied to reduce the number of equations based on the great difference in the rate of fast (binding and unbinding of proteins) versus slow reactions (transcription, translation and protein degradation):(12) Here stands for multiplicity of infection (), and are the rescaled concentrations of and free monomers, is transcriptional rate of when the promoter is bound, is the transcriptional rate of when the promoter is unbound, and and are degradation rates for and proteins respectively.
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