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Interactions between the imputed, unweighted genetic risk score and each of the following risk factors previously shown to be associated with T2D in InterAct were assessed: sex [9], diabetes family history [14], BMI (three levels: <25, 25 to <30, ≥30 kg/m2) [12], WC (three levels: men, <94 cm [34.6 inches], 94 to <102 cm [34.6 to <40 inches], ≥102 cm [≥40 inches]; women, <80 cm [31.5 inches], 80 to <88 cm [31.5 to <35 inches], ≥88 cm [≥35 inches]) [12], age (continuous) [9], physical activity (four levels: inactive, moderately inactive, moderately active, active) [26], and Mediterranean diet score (integer scale from 0–18, included as a continuous variable) [20].
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