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  • , inhibition of PLC, Akt, and ERK decreased CD11c expression in WT cells, but no further decrease was observed in MCP-1-KO cells, suggesting that MCP-1 is required for activation of phospholipase C (PLC), transforming oncogene from Ak strain (Akt), and extracellular signal-regulated kinase (ERK) upon M-CSF stimulation.
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