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  • Inclusion criteria for our review were: (1) longitudinal measurement of the course of depression (2) providing absolute numbers or percentages of recurrence a) diagnosis established with an interview based on state- of the- art depression criteria (e.g. Diagnostic and Statistical Manual of Mental Disorders, DSM-III/III-R/DSM-IV) [12]–[14] or b) with standardized questionnaires that assess depressive symptoms (e.g., Inventory of Depressive Symptomatology, IDS) [15] or -, Hamilton Rating Scale for Depression, HRSD) [16] (3) with a follow-up of at least six months (4) in which data were collected for patients with and without a certain co-morbid chronic somatic illness at the same measurement intervals a) where co-morbid chronic somatic illnesses were assessed either via self-report or b) medical records or c) by a diagnosis of a medical professional.
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