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  • In fact, we observed marked effect on proliferation among three relatively resistant and one sensitive cell lines to gefitinib (KU-7, UM-UC3; UM-UM13) when cells were pre-treated with gefitinib for 24 hs to allow for induction of PPARĪ³ expression compared to when the cells were simultaneous exposure to gefitinib and DIM-C (Figure 8).
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