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  • Inclusion criteria were: (1) mild to moderate neurological disability, but with unimpaired ambulation (Expanded Disability Status Scale [EDSS] ranging from 1.5 to 3.5) [35]; (2) no clinical relapse and no corticosteroid therapy for at least six weeks before inclusion in the study; (3) no diagnosis of major depression, alcohol or drug abuse or other psychiatric disorders according to the DSM-IV criteria.
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