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Post-iPrEx, another email broadcast was sent with an invitation to learn about the study, and the number of members targeted was increased to include all U.S. members (excluding those with self-disclosed HIV infection) given modest enrollment rates from the pre-iPrEx phase: 93 972 members received and opened the emails, 16 715 (17.8%) clicked through to the survey, 6 267 (37.5%) consented to complete a pre-screening questionnaire, 5 399 (86.1%) met eligibility criteria, and 4 558 (84.4%) consented to enroll in the study and have their data analyzed, representing a 27.3% response rate; 1 584 (34.8%) of participants abandoned the study before completion.
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