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  • We compiled a dataset of 330 protein domains involving 370 domain–domain interactions from the database provided by Itzhaki et al. [4] This database was obtained by mapping structurally derived domain–domain interactions onto the cellular protein–protein interaction network of five different organisms (Escherichia coli, Saccharomyces cerevisiae, Caenorhabditis elegans, Drosophila melanogaster, and Homo sapiens).
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