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  • In this proof-of-concept study, we used a systems perspective to conceptualize and investigate treatment-related dynamics (temporal and cross-sectional associations) of symptoms and elements related to the manifestation of a common functional somatic syndrome (FSS), Globus Sensations (GS). We analyzed data from 100 patients (M=47.1 years, SD=14.4 years; 64% female) with GS who received eight sessions of group psychotherapy in the context of a randomized controlled trial (RCT). Symptoms and elements were assessed after each treatment session. We applied a multilevel graphical vector-autoregression (ml GVAR) model approach resulting in three separate, complementary networks (temporal, contemporaneous, and between-subject) for an affective, cognitive, and behavioral dimension, respectively. GS were not temporally associated with any affective, cognitive, and behavioral elements. Temporally, catastrophizing cognitions predicted bodily weakness (r=0.14, p<0.01, 95% confidence interval (CI) [0.04–0.23]) and GS predicted somatic distress (r=0.18, p<0.05, 95% CI [0.04–0.33]). Potential causal pathways between catastrophizing cognitions and bodily weakness as well as GS and somatic distress may reflect treatment-related temporal change processes in patients with GS. Our study illustrates how dynamic NA can be used in the context of outcome research. (xsd:string)
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  • 2023 (xsd:gyear)
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  • 2023 (xsd:gyear)
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  • 10.1038/s41598-023-42186-y ()
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  • 20452322 ()
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  • Treatment-associated network dynamics in patients with globus sensations: a proof-of-concept study (xsd:string)
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  • In Scientific Reports, 13(1), 1-13, 2023 (xsd:string)
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