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  • Angiogenesis is regulated by a plethora of different proteins, including members of the vascular endothelial growth factor (VEGF) family (e.g., VEGF and its receptors, VEGFR-1 and VEGFR-2, placental growth factor [PlGF]) [5], the angiopoietin (Ang) family (e.g., Ang2) [6], and proinflammatory chemokines (e.g., interleukin [IL]-8) [7].
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