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  • In patients with PD, the total burden of WMLs was associated with higher CSF levels of VEGF (β = 0.40, p = 0.004; figure 2D), PlGF (β = 0.42, p = 0.002; figure 2E), and IL-8 (β = 0.24, p = 0.044), as well as with higher VEGF/sVEGFR-1 ratio (β = 0.37, p = 0.004) and PlGF/sVEGFR-1 ratio (β = 0.38, p = 0.003).
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